Tag Archive: dna testing


AdamLanza 150x150 Studying Adam Lanza: Possible Evil Gene?When senseless tragedy strikes, whether it is a natural disaster or an event caused by mankind, it is instinct to search for reasons as to how it happened. Humans feel compelled to understand the processes that lead to these events so that preventative measures can be developed and lives can be saved.

Researchers are asking if it is possible to reduce evil to a genetic code. This process is being further studied to identify an “evil gene” in people like 20 year old, Adam Lanza. He is responsible for shooting his own mother and killing 26 people at Sandy Hook Elementary School in Newton, Connecticut.

Scientific understanding of genetics has come far since Gregor Mendel began working with his pea plants in the 1850s. DNA can be used to map ancestry and as evidence in criminal trials. However, the idea that a gene can be identified to predict and prevent violent crimes is complicated by deeper questions.

Does an Evil Gene Exist?

The existence of a gene that indicates criminally violent tendencies will be difficult to prove—if for no other reason than the small sample size. Thankfully, serial and spree killers make up a very small fraction of the world’s population. If scientists look only at those known to have committed violent crimes instead of conducting random sampling, then they may miss other factors that contribute to the behavior.

AdamLanza2 549x343 custom Studying Adam Lanza: Possible Evil Gene?

If an Evil Gene Exists, How Does it Work?

Scientists already know certain genes increase risk for diseases such as cancer and heart disease. They are also aware that a risk does not equate to a guarantee. A gene which indicates a predisposition to violent behavior might work the same way. It could be a dominant or a recessive trait. It might affect one person more severely than another, causing one person to mercilessly squash every insect they see while another makes headlines for their violent actions. Another possibility is that the gene could be inhibited, or turned off by medication. Identifying the gene, is only the first step of the process. Scientists will need a clear understanding of how it interacts with the rest of the body and whether or not it is a hereditary trait.

If Scientists Discover an Evil Gene, What Can Be Done?

The discovery of a gene that predisposes people to violent behavior could lead to a debate about compulsory screening. It could also add a layer of complexity to legal systems. If the Adam Lanza’s of the world are acting on the whims of a gene, something that cannot be controlled, then punishment for crimes enters the same ethical arena as insanity or intellectual disabilities. Researchers will be called upon to discuss the degree of nature versus nurture when deciding whether or not a violent criminal can be held accountable for their actions.

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DefyYourDNABook 250x422 custom Prevent Rare Diseases with Gene Patch MedicinesThe overall focus of medicine is a concept that has been highly structured for several decades. Many modern day physicians now offer personalized approaches to help fight their patient’s illness. New waves of alternative drugs have been able to effectively target patients with specific needs. Ultimately, these new “personalized drugs” can potentially pose a threat to the thousands of mainstream drugs available today. New DNA-based drugs focus on providing a more effective solution to overcoming and preventing rare diseases.

Dr. Stephen B. Shrewsbury, MD is the author of Defy Your DNA. One of Dr. Shrewsbury’s many goals in writing this book is to provide hope to those faced with a rare genetic disease. Throughout the book, he discusses the introduction of various “gene-patch” medicines. These gene patch therapies will be able to help thousands of Americans identify and prevent diseases before they become ill.

Defy Your DNA offers insight to how specialized drugs can patch up mistakes located in our DNA. The rare diseases that can be adverted include Muscular Dystrophy and Lou Gehrig’s disease. It is reported that these medications will also be able to tackle cancer, asthma and high cholesterol. Shrewsbury is paving the way for a more direct and targeted approach to becoming familiar with your DNA as well as offering a solution to health issues that were previously recognized as terminal.

Shrewsbury has dedicated the book to those who have previously participated in a drug study of some sort. He recognizes that without these brave individuals, new drugs or advances in pharmaceuticals would not be possible. Defy Your DNA begins by discussing the evolution of medicine and where it stands now. Dr. Shrewsbury makes note of how generalized medicine has shifted into a more personal approach.

One of the most interesting chapters would have to be “New Drugs for Bad Bugs” which further explains how new medicines will block harmful viruses. Today, Dr. Shrewsbury has established Shrewd Consulting LLC which encourages and advises biotechnology and biopharmaceutical companies who also seek to develop new drugs which will combat genetic disorders.

StephenShrewsburyMD Prevent Rare Diseases with Gene Patch Medicines

Three main ways on how gene patches will revolutionize medicine, include:

  • They are designed reproducibly and are incredibly accurate, to patch a tiny piece including 30 letters of the human genome’s 3 billion letters. Once the sequences of those letters have been determined, the gene patches can be built quickly.
  • Gene patch medication can target various parts of the human genome. It can prevent and counter rare diseases that are treated poorly or not at all by today’s sophisticated medicines.
  • Once the FDA has gained experience with some of these gene patches, companies developing new ones will use the same basic backbone chemistry, which will allow faster development and path to approval for a wide range of new drugs. This will ensure more medicine is readily available to treat more people; many with challenging diseases who have been neglected until now.

“A number of these drugs currently in research could be submitted to the FDA for final approval in the next year” says Shrewsbury. “A big benefit with this new type of medicine is that the early phase of drug development before clinical trials start takes less time, in some cases, days instead of years. These medications will literally revolutionize healthcare.”

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Violent crimes are among the most horrific events on Earth, but sometimes it gets even worse. The crime itself happens and then another person becomes victim to it. A person’s life can be destroyed or even taken from him or her if authorities accuse and charge the wrong person with the crime. To further compound the tragedy, the families of both the original victim and the person jailed under false accusations may not know that the real criminal is still at large. DNA testing can ultimately prove who is responsible for a given crime investigation.

RandolphA 300x218 Man Found Innocent After DNA Test Randolph Arledge was a victim of a false accusation, charge and conviction. In 1981, Carolyn Armstrong was found dead in Texas from dozens of stab wounds. Randolph was not even 30 years old at the time. Three years later, Randolph was sentenced to 99 years in prison for killing Armstrong. The problem is that he did not do it and there was evidence to prove that fact. He went on to spend 28 years of his 99-year sentence in jail for a crime he did not commit. In February 2013, Arledge was set free. Close to half of his life has been stolen from him, but he got the rest back thanks to modern DNA testing.

When Carolyn Armstrong was found, police also found her car down the road. Her vehicle contained DNA evidence but was useless at the time. Arledge is very lucky that police decided to keep the evidence, since they can usually be discarded in most cases. DNA testing was done more than a decade later and determined that another man was the killer. After a hearing, is when a local judge let Arledge go on bond until the conviction is officially overturned.

When Arledge went to jail, his two children were both under five years old. Currently, they are both adults who grew up without a father. The family is now reunited and Armstrong’s family has the satisfaction of knowing that police definitely have the right man this time. Sadly, that does not get back any of the time Randolph Arledge and his children lost.

It is uncertain just how many people have been incarcerated under wrongful convictions. DNA testing is too late to save hundreds or even thousands of them, but it is not too late to make sure that it happens much less often and never in cases where there is DNA evidence. With reliable companies making it easy for even civilians to get accurate DNA testing, there is no reason police and courts cannot offer the same.

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PrinceHarry 238x300 Prince Harry’s DNA Test to Detect “Ginger Gene” Prince Harry’s antics in Las Vegas last fall understandably enraged members of the royal family. Sowing a few wild oats may not have invoked such ire if Harry had taken care to ensure the event remained private. However, nude photos of the young prince and a bevy of hookers emerged to the delight of media personnel. The indiscretion soon reached the confines of England’s royal palace. Influenced by her board of advisors, the Queen herself supposedly demanded that Harry undergo DNA testing to determine if he was in fact the product of royal blood.

Lady Diana supposedly had an affair with a military officer by the name of James Hewitt. Many questioned whether the alliance produced the young prince. Like Harry, the gentleman dons red hair and fair skin covered in an array of freckles. According to reports, Prince Charles adamantly prohibited any DNA testing that questioned Harry’s heritage.

Prince Harry Test

In honor of the fun-loving royal, Britain’s DNA now offers couples the opportunity of determining the likelihood of producing a red-haired child. Couples interested in the possibility of passing the red hair trait along to offspring need merely submit a saliva sample for DNA testing. Technicians are able to identify the “ginger gene” by analyzing DNA samples. Dr. Jim Wilson, one of the company’s employees explains that having a child with red hair requires carrying one of three variations of the MC1R gene.

If both parents carry the gene variation, they have a 25 percent possibility of having children with red hair regardless of the hair color of the parents. Passed on from one generation to the next, statistics estimate that four out of every 10 people carry the variation. The company plans to offer the “Who Do You Think You Are?” test during a live exhibition at the London Olympia in February.

RedHeadGene 300x187 Prince Harry’s DNA Test to Detect “Ginger Gene”
Questions Answered by DNA Testing

While DNA testing has long been used for determining paternity, evaluating genetic markers provides a variety of information ranging from ancestry to disease predisposition. Analyzing samples supplied by individuals, technicians successfully separate genetic information donated by each parent. Using worldwide databases, laboratory technicians have the ability of determining the point of origin of genetic material spanning back many generations.

Modern DNA testing identifies when individual’s carry genetic markers associated with over two dozen known medical conditions. Genetic information reveals if individuals carry markers associated with aging processes that might include Alzheimer’s or macular degeneration. Testing also indicates when someone has a likelihood of developing seven different types of cancers. The test might additionally determine the possibility of experiencing cardiovascular disease or diabetes. Using this information, patients and physicians may formulate preventative treatments.

Predisposition testing requires that individuals submit the necessary sample in the office of a health care provider. Individuals may submit DNA samples for ancestry or paternity evaluation from the privacy of their home. After purchasing a test kit, clients merely follow the instructions for acquiring the necessary sample, which generally only entails swabbing the inside of the mouth. Once received by the testing laboratory, technicians perform the desired test and send the results back to the client.

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AncestralOrigins 206x300 Discover your Ancestral Origins with DNA Ancestry Testing Ancestral Origins DNA Testing is a way to discover more about your genetic heritage. Every person is born with their own unique DNA. This genetic information remains constant throughout an individual’s lifetime. Each human being’s DNA tells their individual story. It also charts the beginnings of humankind in Africa and the eventual migration of humanity to every part of the globe.

Criteria Used to Determine Your DNA Ancestry

The process of determining your genetic heritage is threefold. Ancestral Origins testing separates the genetic information into three basic areas; populations, indigenous regions and strength estimates.

Populations

Using a color coded rating system; your DNA is compared to all the populations in their system. The color green on the map shows the strongest connection to a specific group and location. The color yellow relates to a significant link to particular areas and populaces and red suggest little or no connection. There are also correlations made to dispersed populations. Dispersed relates to groups of people, who were indigenous to one region, but traveled to another country or continent. This pertains to more recent movements of populations around the world.

Indigenous Regions

This testing reveals an ancient ancestry dating back over 80 thousand years. During the history of humankind there have been notable ancient migrations. One of the first migrations occurred, when people traveled out of Africa and up into Europe, then Asia and eventually to Australia. The last two migrations were to North and South America and the final journey was to the Pacific Islands.

DNAHelix 300x239 Discover your Ancestral Origins with DNA Ancestry Testing
Strength Estimates

This primary evaluation is an estimate of all the populations that are your strongest genetic links. The next assessment shows the most significant connections to indigenous regions. These calculations give a clear overview of all the data, so it is easier to determine your closest genetic matches.

Discovering Your Ancestral Origins

Ancestral DNA testing helps you to appreciate your genetic connection to particular groups and geographic origins. The DNA Ancestry tests can verify genetic relatedness to 14 identified anthropological areas and populaces. GTLDNA.com contains beautifully designed maps and graphs which makes the history and science of ancestral origins easier to appreciate. These individualized prints will make lovely additions your home.

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DNA Predisposition testing can help determine your risk for several diseases that many people suffer from as they age. This particular DNA test has been proven effective by saving lives. Learning whether you are predisposed to certain diseases or medical conditions will allow a physician to treat you before there are any signs of potential illness.

predisposition mainpicture DNA Predisposition Testing Helps Save Lives Across the World

The Genetic Predisposition Health DNA test can determine if you are prone to develop any of 25 different diseases. Any risk that may be determined by this test is compared to the risk of the average population. This genetic test has a 99.9% accuracy level, which is shown as high, medium or low. Of course, additional environmental factors always play a key role in determining an individual’s health.

The diseases of the immune system that are covered by this test include: lupus, Grave’s disease, celiac disease, multiple sclerosis and psoriasis. There are several predictable cardiovascular diseases as well, which are: aneurysms, atrial fibrillation, heart disease, peripheral arterial disease and venous thromboembolism. The predictable cancers include: the bladder, breast, colorectal, gastric, lung, prostate and the skin. Ageing disease are macular degeneration, Alzheimer’s disease, osteoarthritis and rheumatoid arthritis. Finally, general health disease include: obesity, migraine headaches, Type I and II diabetes.

In the UK, a 33 year old writer from “The Sun” decided to take the DNA genetic predisposition test by comparing two laboratories. Both laboratories used the same method of screening by having the client place a few drops of blood on a card, and then placing it in the mail. The similar results were not particularly surprising when compared with the medical history of the writer’s family members for the higher risk diseases. The writer was advised to see a general practitioner to ensure her health was in good standing. Being at a higher risk does not mean you will get the disease or medical condition, as environmental factors play a role in the state of your health.

The writer concluded “Decoding the messages hidden in our genes is thought to be vital to the future of healthcare in the UK.”

Many have become concerned about the results of these tests being made available to employers or insurance companies, which could lead to discrimination. Currently In England, there is a moratorium in place until 2017 that prevents insurance companies from insisting on any disclosure of DNA results.

It is important to understand the difference between genetic diseases and those considered environmental, which is why we recommend using a genetic counselor for the pre and post-test time frame. A trained genetic counselor has the expertise to interpret and explain the results of your DNA test. The results of the test enable one to make any necessary lifestyle changes that could possibly lower the risk of some diseases.

Having a positive result with a genetic predisposition for a disease does not mean that you will definitely develop the disease, but it can certainly cause stress. The test cannot predict the future, but should be used to make healthy lifestyle changes. It is wise to get appropriate medical testing when warranted. For instance, if you have a predisposition for colorectal cancer, a colonoscopy might be warranted at an earlier age. It is recommended that a doctor interpret the results and complete a physical assessment to give you the best medical advice to achieve optimal health.

Can this test help save you and your family? Order your DNA predisposition test today to find out which diseases and medical conditions you are predisposed to.

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Recent media coverage has enclosed that Kim Kardashian is pregnant. Many onlookers are now wondering if Kardashian’s boyfriend Kanye West will demand a paternity test. Other skeptics suggest that West will demand that Kim takes a paternity test in order to prove that the child she is carrying is definitely his. Paternity testing has become a ubiquitous part of 2013, especially after the death of NFL star Jovan Belcher.  However, this does not seem to be the case for “Kimye” – not yet at least.

Kim Kardashian Kanye West Baby   Kim Kardashian Pregnant! Will Kanye West Demand A Paternity Test?
Of course, this isn’t the first bit of drama that the young model and has been involved with. We all witnessed her short-lived marriage to Kris Humphries, which lasted just 72 days before the starlet filed for divorce. In fact, the two are technically still  married in the state of California.

Still, Kim Kardashian has been vocal that she is not the only person who is expecting a child. In an announcement to the press she told readers of her blog that she and Kanye are expecting a baby. The socialite seemed excited for the prospect of her future, even though she and Kanye have only been dating for a short time.

Undoubtedly, this recent turn of events will add fuel to Kris Humphries’ fire. He claims that Kim married him simply to promote her brand and get television ratings, and the speed with which his ex bride has moved on would seem to support this idea. Humphries and Kardashian will head back to the courtroom in February 2013 to hash things out, and Kim better hope her ex will play ball. However, experts suggest that basketball star Kris Humphries will still be married until the end of June, which gives him time to play with the team on the court.

Rumors are swirling that Kim Kardashian is putting the heat on her own lawyers to wrap things up as quickly as possible, but while she’s feeling the heat from playing with fire, Kanye West doesn’t seem perturbed at this unexpected pregnancy. Kanye and Kim happily celebrated their good news with their families as the beginning of the year. Kanye’s father and Kim’s mother both made appearances, while Kim’s siblings congratulated them on Twitter.

kim and kanye on new years  Kim Kardashian Pregnant! Will Kanye West Demand A Paternity Test?

Few people think she and Kanye are ready to tie the knot. Given her estrangement from Kris Humphries, Kim Kardashian would likely list Kanye as the father of her baby, which is expected in early June. Signing the paperwork would list Kanye as the legal, as well as biological father, of Kim’s baby. However, only time will tell if how Mr. West feels about a paternity test.

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Benefits of DNA Testing

The most accurate way for physicians to diagnose genetic disorders in newborn infants is DNA testing, which is the thorough examination of the DNA molecule. Children’s Mercy Hospital of Kansas City, MO, is using a new test that provides results in a couple of days versus the typical weeks or even months in the past. The test is designed to specifically identify disease causing mutations.

This new DNA examination is not in widespread use at this time as research is ongoing. The facts are one in 20 newborns in neonatal intensive care units have a genetic disease. Faulty genes have been found in 3,500 of the 7,500 known genetic diseases.

Since the completion of the Human Genome Project Analysis a large amount of data analysis will be ongoing for many years. In this project approximately 20,000 to 25,000 genes were identified, along with the sequencing of the 3 billion chemical base pairs that make up human DNA.

There are numerous accredited laboratories where it is possible to get accurate DNA testing for paternity testing. When looking for a laboratory to have DNA testing, it is important to seek out one that has several accreditations from governing agencies.

baby04 Infant DNA Tests Speed Diagnosis of Rare Diseases

Some of the accrediting agencies to seek out are:

  • American Association of Blood Banks, which requires a rigorous review with an inspection of the testing processes and the laboratory.
  • National Association of Testing Authorities (NATA), which is the most difficult accreditation to obtain due to its difficult quality and security requirements.
  • Safe Harbor requires data protection, providing privacy protection for the European Union.
  • ISO 17025 accreditation assures technical competence with the calibrations and testing labs.
  • A2LA accreditation system is the largest multi-discipline system in the United States, which is recognized by Accreditation Bodies in the European Union and other international countries.

DNA tests only require a buccal swab, which is painless swab from inside of the cheek from an infant or adult. The testing may also be completed with a blood
sample from a finger prick. DNA sampling for a paternity test, particularly if it is legally binding, requires a swab from the mother, child and alleged father. This is the most accurate way to determine paternity and a good laboratory will require 16 identity markers for accuracy. One of those markers determines the sex of the person. Accuracy can reach 99.99999 percent.

There are many types of tests that may be ordered from the laboratory. For instance, a DNA Predisposition Test reveals the predisposition for 25 different diseases and conditions. DNA testing can be completed to look for ancestral origins. An Infidelity DNA Test can test a wide range of garments or objects for DNA. There is a Zygosity DNA Twin that will confirm whether twins are fraternal or identical. Furthermore, there are tests for grandparents, aunts and uncles. Prenatal paternity testing may also be completed before birth. There is also an Immigration DNA Test and a Missing Parent Test that may help law enforcement.

Finally, two people may get a DNA test to see if they are related. DNA testing may be done through the mail and is confidential, with the results being mailed in a plain envelope. Accuracy is guaranteed with an accredited laboratory and DNA testing if very affordable.

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Damon Thibodeaux dna prisoner 532x357 custom DNA Evidence Exonerates 300th Prisoner

The 300th prisoner,, was just released from prison after being found innocent based on DNA evidence. This man spent sixteen years in prison. Damon Thibodeaux confessed to rape and murder after nine hours of interrogation, which was untapped. Finally in 2007, his legal team persuaded the Jefferson Parrish County District Attorney to reopen the case after the team agreed to share the expenses. The resulting evidence proved the girl had not been raped, and the DNA evidence did not belong to Mr. Thibodeaux.

The Innocence Project, founded in 1992, by Barry C. Scheck and Peter J. Neufeld, was established to assist prisoners to be released from prison when they could be proven innocent through DNA testing. Out of the 300 prisoners released, seventeen were on death row, including Mr. Thibodeaux. The people who have been released spent an average of 13 years in prison. Many other attorneys are also working on freeing innocent prisoners, including law students working on the University of Chicago Law School’s Exoneration Project.

This organization is a public organization with the goal of reforming the criminal justice system through DNA testing. They are evaluating anywhere frm 6,000 to 8,000 potential cases constantly, and they receive approximately 3,000 requests for help annually. Their website publishes the number of exonerees and their race.

At this time the released exonerees consist of the following races:

  • 187 African Americans
  • 85 Caucasians
  • 21 Latinos
  • 2 Asian Americans
  • 5 whose race is unknown

In 146 of these cases the true perpetrators have been identified. Another interesting fact is that 60 percent of the people exonerated have been financially compensated since states have passed laws to compensate people who are wrongly incarcerated.

Texas leads the nation in exonerating wrongly convicted prisoners. They also have a new law for compensation. Each exoneree receives $80,000 for each year they spent behind bars. In addition, they also receive an annuity between $40,000 and $50,000 annually, which makes this the most generous reimbursement package in the nation.

The number of innocent people being released has proven that wrongful convictions happen much more frequently than previously thought, and some states will be voting on abolishing the death penalty for this reason.

There are several reasons people are wrongly convicted, but the primary reason is misleading eyewitness testimony. This proved to be a factor in 72 percent of the overturned cases, with 40 percent of the cases involving cross racial identification.

In approximately 50 percent of the cases, improper forensic science was part of the problem, with such problems as errors in hair microscopy, bite mark comparisons, shoe print comparisons and firearm tool marking analysis.

In approximately 27 percent of the cases, there were false confessions and incriminating statements made by the defendant following interrogations. The Innocence Project is pushing police departments to record all interrogations to prevent coercion and to have an accurate record.

The last contributing factor is false informants found in 18 percent of the cases. Informants often receive special treatment for their testimony, which is an incentive to lie.

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genealogy web Why Keeping Track of Family Genealogy is ImportantEstablishing accurate genealogy can be critical for a number of individuals. One of the top reasons is actually because of the advances in genetic science that permits genealogical testing to be done in the first place. Not only can DNA be used to establish lineage, it is also routinely used to show potential health issues that can rise later in life. Establishing an accurate lineage helps when it comes time to putting together a family medical history.

Pressure from family and culture has produced many children who grow into adulthood under the false impression of whom their parents are . This can lead to problems later on if a health issue arises with the individual or even their progeny. The first papers filled out in any medical facility include in-depth questions about family medical history. This can only be accomplished with accuracy if one’s own genealogy is known to be true.

Our current technological age has many families losing records and keepsakes that family members just a generation or two earlier kept close track of. Most data today is electronic and can be lost in just one second. Earlier generations kept written records along with sharing information orally about ancestors. Family Bibles used to be sold that had whole sections for family to record highly detailed family history in them. This has fallen out of fashion.

Establishing genealogy through simple and inexpensive DNA testing empowers people by letting them know for sure where they have come from. A simple paternity test establishes who one’s father is. That knowledge can be used to accomplish everything from introducing a whole new set of biological relatives to answering questions concerning certain traits, characteristics and health issues. The same genetic science that established parentage can then be used to show much more. Some do not wish to know this information, and that is perfectly fine. However, whenever the questions beg to be answered, there is a way of finding out for sure. Inexpensive paternity testing is 99.999 percent accurate for showing whom one’s father is and 100 percent accurate for excluding those who are not. There is also testing to prove or disprove whom one’s mother is. The information is so accurate that it is considered to be binding evidence in a court of law.

No blood testing is needed for paternity tests. Only easy to obtain swabs of the inside of the mouth are needed. This makes it easy for anyone to do since the DNA sampling does not involve any invasive procedure such as a needle to get a blood sample. The cells that line the mouth contain DNA that is tested to prove or disprove lineage. The testing is discreet and fast. The questions that have been wondered about for a long time can now finally be answered.

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